Product Name: Human Siglec-3 / CD33 Antibody (IMGN779, Research Use)
Catalog Number: NBR-0871
Target Name: Siglec-3 / CD33
Trade Name: IMGN779
Antibody Drug Description: IMGN779 is a next-generation anti-CD33 ADC with anovel DNA-alkylating IGN payloadand a cleavable s-SPDB linker.Preclinical studies suggest potentantitumor activity and improvedsafety and tolerability compared withDNA-crosslinking payloads, allowingfor repeat dosing Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  CD22
Synonyms: SIGLEC-2; SIGLEC2
Target Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45.
Ensembl: ENSG00000012124
Uniprot:  P20273