【Introduction】
Product Name: Human PD-L1 Antibody (MDX-1105, Research Use)
Catalog Number: NBR-0071
Target Name: PD-L1
Trade Name: MDX-1105
Antibody Drug Description: BMS-936559 (MDX-1105) is a PD-1 (PDCD1) human monoclonal antibody, which blocks the binding of PD-L1 (CD274) resulting in a T-cell mediated immune response and possible tumor regression.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PD-L1
Synonyms: CD274; B7H1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7