Product Name: Human Tau Antibody (Semorinemab, Research Use)
Catalog Number: NBR-0288
Target Name: Tau
Trade Name: Semorinemab
Antibody Drug Description: Semorinemab is an investigational monoclonal anti-tau antibody that targets the N-terminal portion of the Tau protein, and is designed to bind to Tau and slow its spread between neurons. In tauopathies such as AD, Tau misfolds and forms tangles, which cause cell damage and ultimately neuronal death.  Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: Tau
Synonyms: DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PPND; PPP1R103; tau
Target Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity . The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.
Ensembl: ENSG00000186868
Uniprot: P10636