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Product Name Human RGM C Antibody (DISC-0974, Research Use)
Catalog Number NBR-0365
Alias/Synonyms
Appearance Transparent Liquid
Molecule Weight 150kDa
CAS N/A
Solubility Water, PBS, TBS Buffer,etc.
Storage Temp. -80℃
Shelf Life see COA
Additional info 1 CHO Expressed
Additional info 2 Ab. Isotype - IgG
Catalog Numbe Size Price Inventory Level  
NBR-0365-100UG 100ug $95 Inquire
NBR-0365-1MG 1mg $650 Inquire
NBR-0365-5MG 5mg $1395 Inquire



【Introduction】
Product Name: Human RGM C Antibody (DISC-0974, Research Use)
Catalog Number: NBR-0365
Target Name: RGM C
Trade Name: DISC-0974
Antibody Drug Description: DISC-0974 is a first-in-class monoclonal antibody agains the mojuvelin (HJV) to suppress the production of hepcidin and enhance iron levels to treat anemia of inflammation.DISC-0974 binds to and prevents signaling through the HJV pathway, resulting in suppression of hepcidin expression which improves availability of iron for erythropoiesis. 

【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

 
【Gene Information】
Gene Name: RGM C
Synonyms: 
Target Description: Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses.
Ensembl: 
Uniprot: 
 
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