【Introduction】
Product Name: Human RGM C Antibody (DISC-0974, Research Use)
Catalog Number: NBR-0365
Target Name: RGM C
Trade Name: DISC-0974
Antibody Drug Description: DISC-0974 is a first-in-class monoclonal antibody agains the mojuvelin (HJV) to suppress the production of hepcidin and enhance iron levels to treat anemia of inflammation.DISC-0974 binds to and prevents signaling through the HJV pathway, resulting in suppression of hepcidin expression which improves availability of iron for erythropoiesis.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: RGM C
Synonyms:
Target Description: Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses.
Ensembl:
Uniprot: