【Introduction】
Product Name: Human TNFRSF10A / TRAILR1 / CD261 Antibody (Mapatumumab, Research Use)
Catalog Number: NBR-0483
Target Name: TNFRSF10A / TRAILR1 / CD261
Trade Name: Mapatumumab
Antibody Drug Description: Mapatumumab is a fully human agonistic monoclonal antibody that selectively targets TRAIL-R1 receptors expressed on the cell surface of many tumors.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TNFRSF10A
Synonyms: Apo2; CD261; DR4; TRAILR-1; TRAILR1
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL 1. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000104689
Uniprot: O00220