【Introduction】
Product Name: Human PDCD1 / PD-1 / CD279 Antibody (Geptanolimab, Research Use)
Catalog Number: NBR-0652
Target Name: PDCD1 / PD-1 / CD279
Trade Name: Geptanolimab
Antibody Drug Description: Geptanolimab (also known as APL 501, CBT 501or GB 226) is an immunoglobulin G4 (IgG4) humanised monoclonal antibody against the programmable death-1 (PD-1).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PDCD1
Synonyms: PD1; CD279; HSLE1; SLEB2; HPD-1
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116