
【Introduction】
Product Name: Human IL-6 / IFNb2 Antibody (Siltuximab, Research Use)
Catalog Number: NBR-0768
Target Name: IL-6 / IFNb2
Trade Name: Siltuximab
Antibody Drug Description: Siltuximab is a chimeric monoclonal antibody-targeting IL-6 and being investigated for the treatment of both solid tumors (renal cell, prostate, and ovarian cancers) and liquid tumors.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-6
Synonyms: IL-6; IFNB2; BSF2; HGF; HSF; BSF-2; CDF
Target Description: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable).
Ensembl: ENSG00000136244
Uniprot: P05231