Product Name: Human IL-6 / IFNb2 Antibody (Olokizumab, Research Use)
Catalog Number: NBR-0774
Target Name: IL-6 / IFNb2
Trade Name: Olokizumab
Antibody Drug Description: Olokizumab is a humanized monoclonal antibody that represses the IL-6 pathway by attaching to the 3rd attachment site of IL-6 and blocking its interaction with gp130. It has been previously used as an anti-inflammatory agent for the treatment of RA patients that did not show adequate response to TNF- inhibitors . Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-6
Synonyms: IL-6; IFNB2; BSF2; HGF; HSF; BSF-2; CDF
Target Description: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable).
Ensembl: ENSG00000136244
Uniprot:  P05231