
【Introduction】
Product Name: Human Integrin aV / ITGAV / CD51 Antibody (Abituzumab, Research Use)
Catalog Number: NBR-0782
Target Name: Integrin aV / ITGAV / CD51
Trade Name: Abituzumab
Antibody Drug Description: Abituzumab(EMD-525797,DI17E6)is a new, humanized lgG (2)monoclonal antibody specificallydirected against the alpha (nu)subunit of human integrin receptorswhich is currently in phase Il clinicaltrials for the treatment of metastaticcolorectal and metastatic castration-resistant prostate cancers.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ITGAV
Synonyms: CD51; MSK8; VNRA; VTNR
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF.
Ensembl: ENSG00000138448
Uniprot: P06756