Product Name: Human Integrin aVb3 (ITGAV & ITGB3) Antibody (Etaracizumab, Research Use)
Catalog Number: NBR-0784
Target Name: Integrin aVb3 (ITGAV & ITGB3)
Trade Name: Etaracizumab
Antibody Drug Description: Etaracizumab (LM 609) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab inhibits angiogenesis and melanoma tumor growth. Etaracizumab can be used to research anticancer. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ITGAV & ITGB3
Synonyms: CD51; MSK8; VNRA; VTNR; CD61; GP3A; GPIIIa
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin.
Ensembl:  ENSG00000138448; ENSG00000259207
Uniprot:  P06756; P05106