
【Introduction】
Product Name: Human oxLDL Antibody (Orticumab, Research Use)
Catalog Number: NBR-0796
Target Name: oxLDL
Trade Name: Orticumab
Antibody Drug Description: Orticumab is a fully-human monoclonal antibody against a specific oxidized LDL epitope, malondialdehyde-modified apolipoproteinB-100 (MDA-apoB-100).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: OLR1
Synonyms: CLEC8A; LOX-1; SCARE1
Target Description: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis.
Ensembl: ENSG00000173391
Uniprot: P78380