【产品概况】
产品名称:Human IL-18 Antibody (GSK 1070806, Research Use)
产品编号:NBR-0049
针对靶点:IL-18
抗体药商品名:GSK 1070806
抗体药描述:GSK1070806, an anti-IL18 monoclonal antibody, neutralizes activated (mature) IL18 released from damaged cells following inflammasome activation.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-18
Synonyms: IL1F4; IL-18; IGIF; IL-1g
Target Description: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators .
Ensembl: ENSG00000150782
Uniprot: Q14116