产品名称：Human BCMA Antibody (Belantamab, Research Use)
产品编号：NBR-0129
针对靶点：BCMA
抗体药商品名：Belantamab
抗体药描述：Belantamab mafodotin is a humanized IgG1κ monoclonal antibody against the B-cell maturation antigen (BCMA) conjugated with a cytotoxic agent, maleimidocaproyl monomethyl auristatin F (mcMMAF). The antibody-drug conjugate binds to BCMA on myeloma cell surfaces causing cell cycle arrest and inducing antibody-dependent cellular cytotoxicity.Belantamab mafodotin is a medication for the treatment of relapsed and refractory multiple myeloma. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: BCMA
Synonyms: BCM; TNFRSF13A; CD269; BCMA
Target Description: TNFRSF17 (TNF Receptor Superfamily Member 17) is a Protein Coding gene. Diseases associated with TNFRSF17 include Lymphoma and Macroglobulinemia. Among its related pathways are TGF-Beta Pathway and MIF Mediated Glucocorticoid Regulation. Gene Ontology (GO) annotations related to this gene include signaling receptor activity. An important paralog of this gene is TNFRSF13C.
Ensembl: ENSG00000048462
Uniprot: Q02223