产品名称：Human IL-1RL2 Antibody (Spesolimab, Research Use)
产品编号：NBR-0215
针对靶点：IL-1RL2
抗体药商品名：Spesolimab
抗体药描述：Spesolimab is a novel, humanized, selective antibody that blocks the activation of the interleukin-36 receptor (IL-36R), a signaling pathway within the immune system shown to be involved in the pathogeneses of several autoimmune diseases, including GPP. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: IL-1RL2
Synonyms: IL1R-rp2; IL1RRP2
Target Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity).
Ensembl: ENSG00000115598 
Uniprot: Q9HB29