产品名称：Human Nogo-A Antibody (Ozanezumab, Research Use)
产品编号：NBR-0258
针对靶点：Nogo-A
抗体药商品名：Ozanezumab
抗体药描述：Ozanezumab is a monoclonal antibody designed for the treatment of ALS and multiple sclerosis.Ozanezumab targets a protein called Neurite Outgrowth Inhibitor (NOGO-A) or Reticulon 4. NOGO-A is a protein that in humans is encoded by the RTN4 gene that has been identified as an inhibitor of neurite outgrowth specific to the central nervous system. NOGO-A is found at higher than normal levels in persons with MND. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: Nogo-A
Synonyms: ASY; KIAA0886; NOGO; NSP-CL
Target Description: Immune inhibitory receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia molecules. 
Ensembl: ENSG00000115310
Uniprot: Q9NQC3