产品名称：Human RSPO3 Antibody (Rosmantuzumab, Research Use)
产品编号：NBR-0278
针对靶点：RSPO3
抗体药商品名：Rosmantuzumab
抗体药描述：Rosmantuzumab is a humanized monoclonal antibody against Human RSPO3 that can be potentially used in the treatment of Advanced Relapsed Tumor, Refractory Solid Tumors. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: RSPO3
Synonyms: FLJ14440; THSD2
Target Description: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.
Ensembl: ENSG00000146374
Uniprot: Q9BXY4