产品名称：Human Tau Antibody (Semorinemab, Research Use)
产品编号：NBR-0288
针对靶点：Tau
抗体药商品名：Semorinemab
抗体药描述：Semorinemab is an investigational monoclonal anti-tau antibody that targets the N-terminal portion of the Tau protein, and is designed to bind to Tau and slow its spread between neurons. In tauopathies such as AD, Tau misfolds and forms tangles, which cause cell damage and ultimately neuronal death.  产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: Tau
Synonyms: DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PPND; PPP1R103; tau
Target Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity . The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.
Ensembl: ENSG00000186868
Uniprot: P10636