Human ILT7 Antibody (Daxdilimab, Research Use)

产品名称	Human ILT7 Antibody (Daxdilimab, Research Use)
目录号	NBR-0319
别名	CD85g; ILT7
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0319-100UG	100ug	￥550	请咨询
NBR-0319-1MG	1mg	￥3500	请咨询
NBR-0319-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human ILT7 Antibody (Daxdilimab, Research Use)
产品编号：NBR-0319
针对靶点：ILT7
抗体药商品名：Daxdilimab
抗体药描述：Daxdilimab (HZN-7734) is an anti-ILT7 human monoclonal antibody that depletes certain dendritic cells. Depleting these cells may interrupt the cycle of inflammation that causes tissue damage in a variety of autoimmune conditions.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: ILT7
Synonyms: CD85g; ILT7
Target Description: Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G 1, 2. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Ensembl: ENSG00000239961
Uniprot: P59901