产品名称：Human IL-6 / IFNb2 Antibody (MEDI 5117, Research Use)
产品编号：NBR-0765
针对靶点：IL-6 / IFNb2
抗体药商品名：MEDI 5117
抗体药描述：MEDI5117 is a monoclonal antibody developed from a half-life–extended antibody using the YTE platform. MEDI5117 inhibited IL6 signaling and suppressed the growth of lung, breast, and ovarian tumor cells in vitro and in vivo with higher potency than siltuximab. Inhibition of tumor growth was significantly increased when MEDI5117 was used in combination with gefitinib, taxanes, or other chemotherapeutics. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: IL-6
Synonyms: IL-6; IFNB2; BSF2; HGF; HSF; BSF-2; CDF
Target Description: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable).
Ensembl: ENSG00000136244
Uniprot:  P05231