Product Name: Human CD45 Antibody (Apamistamab, Research Use)
Catalog Number: NBR-0348
Target Name: CD45
Trade Name: Apamistamab
Antibody Drug Description: Apamistamab (Iomab-B) is a targeted therapy being developed for AML, comprised of a monoclonal antibody that is connected to radioactive material (making it a radiolabeled antibody).apamistamab (Iomab-B) is currently being studied in the SIERRA clinical trial. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD45
Synonyms: CD45; GP180; LCA; T200
Target Description: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Ensembl: ENSG00000081237 
Uniprot: P08575