
【Introduction】
Product Name: Human Integrin A4 & B7 Antibody ( Vedolizumab, Research Use)
Catalog Number: NBR-0350
Target Name: Integrin A4 & B7
Trade Name: Vedolizumab
Antibody Drug Description: Vedolizumab is a humanized monoclonal antibody that was developed to reduce lymphocyte trafficking to the intestine by specifically targeting the α4β7 heterodimer, which is expressed on the surface of gut-specific lymphocytes.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Integrin A4 & B7
Synonyms: CD49D
Target Description: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1.
Ensembl: ENSG00000115232
Uniprot: P13612