
【Introduction】
Product Name: Human CB1 / CNR1 Antibody (Nimacimab, Research Use)
Catalog Number: NBR-0537
Target Name: CB1 / CNR1
Trade Name: Nimacimab
Antibody Drug Description: Nimacimab is the first and only known clinical stage negative-allosteric modulating antibody to the CB1 receptor in clinical trials. Nimacimab is a multi-modal therapeutic candidate with anti-fibrotic, anti-inflammatory, and beneficial metabolic mechanisms of action.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CNR1
Synonyms: CANN6; CB-R; CB1; CB1A; CB1K5; CNR
Target Description: G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrahydrocannabinol (THC).
Ensembl: ENSG00000118432
Uniprot: P21554