
【Introduction】
Product Name: Human IGF1R / CD221 Antibody (Dalotuzumab, Research Use)
Catalog Number: NBR-0567
Target Name: IGF1R / CD221
Trade Name: Dalotuzumab
Antibody Drug Description: Dalotuzumab (MK-0646) is an anti-IGF-1R IgG1 antibody that has been evaluated as a single agent in a phase 2 trial of NET patients.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IGF1R
Synonyms: CD221; IGFIR; IGFR; JTK13; MGC18216
Target Description: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity.
Ensembl: ENSG00000140443
Uniprot: ENSG00000140443