
【Introduction】
Product Name: Human CD47 Antibody (Ligufalimab, Research Use)
Catalog Number: NBR-0581
Target Name: CD47
Trade Name: Ligufalimab
Antibody Drug Description: Ligufalimab, also known as AK117, is a humanized IgG4 monoclonal antibody with a unique structure. Ligufalimab could effectively eliminate RBC hemagglutination and anemia, and induce robust macrophage-mediated phagocytosis of cancer cells, and improve the antitumor efficacy without the requirement of a lower 'priming' dose to prevent anemia.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD47
Synonyms: IAP; MER6; OA3
Target Description: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus.
Ensembl: ENSG00000196776
Uniprot: Q08722