Product Name: Human TIGIT Antibody (Domvanalimab, Research Use)
Catalog Number: NBR-0588
Target Name: TIGIT
Trade Name: Domvanalimab
Antibody Drug Description: Domvanalimab, an anti-TIGIT antibody, showed clinically meaningful results as an Fc-silent anti-TIGIT/anti-PD-1 combination therapy for patients with first-line metastatic non-small cell lung cancer (NSCLC) at a fourth interim analysis. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TIGIT
Synonyms: VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. 
Ensembl: ENSG00000181847
Uniprot: Q495A1