Product Name: Human Amyloid Beta Antibody (Donanemab, Research Use)
Catalog Number: NBR-0589
Target Name: Amyloid Beta
Trade Name: Donanemab
Antibody Drug Description: Donanemab, aka N3pG, is a humanized IgG1 monoclonal antibody developed from mouse mE8-IgG2a. This biologic drug recognizes Aβ(p3-42), a pyroglutamate form of Aβ that is aggregated in amyloid plaques. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: Amyloid Beta
Synonyms: Alpha-SAPP; AD1
Target Description: APP (Amyloid Beta Precursor Protein) is a Protein Coding gene. Diseases associated with APP include Cerebral Amyloid Angiopathy, App-Related and Alzheimer Disease, Familial, 1. Among its related pathways are MyD88 dependent cascade initiated on endosome and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include identical protein binding and enzyme binding. An important paralog of this gene is APLP2.
Ensembl:  ENSG00000142192
Uniprot:  P05067