Product Name: Human PDCD1 / PD-1 / CD279 Antibody (Dostarlimab, Research Use)
Catalog Number: NBR-0591
Target Name: PDCD1 / PD-1 / CD279
Trade Name: Dostarlimab
Antibody Drug Description: Dostarlimab is a new drug previously used to treat endometrial cancers and has a mechanism of action that is in accordance with other PD-1/PD-L1 inhibitors. A recent clinical trial has found Dostarlimab to cure 100% of the CRC patients who were given this drug while also showing no adverse events of grade 3 or higher in any patient. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD279
Synonyms: PD1; CD279; HSLE1
Target Description: PDCD1 (Programmed Cell Death 1) is a Protein Coding gene. Diseases associated with PDCD1 include Systemic Lupus Erythematosus 2 and Multiple Sclerosis. Among its related pathways are Disease and SARS-CoV-2 Infection. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity.
Ensembl: ENSG00000188389
Uniprot: Q15116