
【Introduction】
Product Name: Human CEACAM5 / CEA / CD66e Antibody (Tusamitamab, Research Use)
Catalog Number: NBR-0600
Target Name: CEACAM5 / CEA / CD66e
Trade Name: Tusamitamab
Antibody Drug Description: Tusamitamab ravtansine is a potential first-in-class antibody-drug conjugate (ADC) targeting CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5), a cell-surface glycoprotein that is highly expressed in non-small cell lung cancer (NSCLC), gastric cancer and other cancers.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD66e
Synonyms: CD66e; CEA
Target Description: CEACAM5 (CEA Cell Adhesion Molecule 5) is a Protein Coding gene. Diseases associated with CEACAM5 include Bile Duct Cancer and Lung Cancer. Among its related pathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GPI anchor binding. An important paralog of this gene is CEACAM1.
Ensembl: ENSG00000105388
Uniprot: P06731