
【Introduction】
Product Name: Human PCSK9 Antibody (Ebronucimab, Research Use)
Catalog Number: NBR-0601
Target Name: PCSK9
Trade Name: Ebronucimab
Antibody Drug Description: Ebronucimab (AK102) is a novel fully human immunoglobulin G1 (IgG1) monoclonal antibody against PCSK9.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PCSK9
Synonyms: NARC-1; FH3; HCHOLA3
Target Description: PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) is a Protein Coding gene. Diseases associated with PCSK9 include Hypercholesterolemia, Familial, 3 and Homozygous Familial Hypercholesterolemia. Among its related pathways are Plasma lipoprotein assembly, remodeling, and clearance and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). Gene Ontology (GO) annotations related to this gene include RNA binding and protein self-association. An important paralog of this gene is TPP2
Ensembl: ENSG00000169174
Uniprot: Q8NBP7