
【Introduction】
Product Name: Human Complement Factor D Antibody (Lampalizumab, Research Use)
Catalog Number: NBR-0611
Target Name: Complement Factor
Trade Name: DLampalizumab
Antibody Drug Description: Lampalizumab (INN) is an antigen-binding fragment of a humanized monoclonal antibody that binds to complement factor D; it was developed as a potential treatment of geographic atrophy (atrophy of the retinal cells, retinal pigment epithelium, and choriocapillaris) secondary to age-related macular degeneration.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: Complement Factor D
Synonyms: ADN; PFD; DF
Target Description: CFD (Complement Factor D) is a Protein Coding gene. Diseases associated with CFD include Complement Factor D Deficiency and Meningococcemia. Among its related pathways are Initial triggering of complement and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is F12.
Ensembl: ENSG00000197766
Uniprot: P00746