Product Name:

NebuSelect™ Recombinant Human SMPD1, His-tag

Catalog#:

NBL-240454

Description:

NebuSelect™ Recombinant Human SMPD1, His-tag(Cat#NBL-240454) is expressed in Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met1-Pro628.

Species:

Human

Expression System:

Baculovirus-Insect Cells

Molecular Weight: 

The protein has a predicted MW of 66.53 kDa. Due to glycosylation, the protein migrates to 67-70 kDa based on Bis-Tris PAGE result.

Target Name:

SMPD1

Target Information:

Sphingomyelin phosphodiesterase 1 (SMPD1) converts sphingomyelin into ceramide and phosphocholine; hence, loss of SMPD1 function causes abnormal accumulation of sphingomyelin in lysosomes, which results in the lipid-storage disorder Niemann-Pick disease (types A and B). SMPD1 activity is dependent on zinc, which is coordinated at the active site of the enzyme.

Amino Acid Sequence: 

Met1-Pro628

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.