Product Name:

NebuSelect™ Recombinant Human Latent GDF-8, His-tag

Catalog#:

NBL-241153

Description:

NebuSelect™ Recombinant Human Latent GDF-8, His-tag(Cat#NBL-241153) is expressed in HEK293 with His tag at the N-terminus.It contains Asn24-Ser375.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.19 kDa. Due to glycosylation, the protein migrates to 35-40 kDa and 45-55 kDa based on Bis-Tris PAGE result.

Target Name:

Latent GDF-8

Target Information:

Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.

Amino Acid Sequence: 

Asn24-Ser375

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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