Product Name:

NebuSelect™ Recombinant Human Nectin-3/CD113, hFc-tag

Catalog#:

NBL-241202

Description:

NebuSelect™ Recombinant Human Nectin-3/CD113, hFc-tag(Cat#NBL-241202) is expressed in HEK293 with hFc tag at the C-terminus.It contains Gly58-Asp400.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 63.63 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

Nectin-3/CD113

Target Information:

The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino acids (aa) in length. It contains an extended signal sequence of 57 aa, an extracellular domain (ECD) of 347 aa, a transmembrane segment of 21 aa (aa 405-425), and a cytoplasmic region of 124 amino acids.

Amino Acid Sequence: 

Gly58-Asp400

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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