Product Name:

NebuSelect™ Recombinant Human Latent Activin A, His-tag

Catalog#:

NBL-241249

Description:

NebuSelect™ Recombinant Human Latent Activin A, His-tag(Cat#NBL-241249) is expressed in HEK293 with His tag at the N-terminus.It contains Ser21-Ser426.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 13.0 kDa (mature form) and 32.0 kDa (pro form). Due to glycosylation and interchain disulfide bond, the protein migrates to 15 kDa (mature form) and 40-50 kDa (pro form) under reduced (R) condition based on Bis-Tris PAGE result.

Target Name:

Latent Activin A

Target Information:

Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.

Amino Acid Sequence: 

Ser21-Ser426

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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