Product Name:

NebuSelect™ Recombinant Human ACVR1/Activin RI, hFc-tag

Catalog#:

NBL-241270

Description:

NebuSelect™ Recombinant Human ACVR1/Activin RI, hFc-tag(Cat#NBL-241270) is expressed in HEK293 with hFc tag at the C-terminus.It contains Met21-Glu123.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 37.43 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.

Target Name:

ACVR1/ALK-2

Target Information:

Activin A receptor type I (ACVR1), a transmembrane serine/threonine kinase, belongs to the transforming growth factor-β superfamily, which signals via phosphorylating the downstream effectors and SMAD transcription factors. Genetic variation in ACVR1 has been associated with a rare disease, fibrodysplasia ossificans progressive, and its somatic alteration is reported in rare cancer diffuse intrinsic pontine glioma.

Amino Acid Sequence: 

Met21-Glu123

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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