Product Name:

NebuSelect™ Recombinant Human NPC2, His-tag

Catalog#:

NBL-241320

Description:

NebuSelect™ Recombinant Human NPC2, His-tag(Cat#NBL-241320) is expressed in HEK293 with His tag at the C-terminus.It contains Glu20-Leu151.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 15.67 kDa. Due to glycosylation, the protein migrates to 21-24 kDa and 27-35 kDa kDa based on Bis-Tris PAGE result.

Target Name:

NPC2

Target Information:

The Niemann Pick type C (NPC) proteins, NPC1 and NPC2, are involved in the lysosomal storage disease, NPC disease. The formation of a NPC1⁻NPC2 protein⁻protein complex is believed to be necessary for the transfer of cholesterol and lipids out of the late endosomal (LE)/lysosomal (Lys) compartments. Mutations in either NPC1 or NPC2 can lead to an accumulation of cholesterol and lipids in the LE/Lys, the primary phenotype of the NPC disease.

Amino Acid Sequence: 

Glu20-Leu151

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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