Product Name:

NebuSelect™ Recombinant Human MUC18/CD146, His-tag

Catalog#:

NBL-242279

Description:

NebuSelect™ Recombinant Human MUC18/CD146, His-tag(Cat#NBL-242279) is expressed in HEK293 with His tag at the C-Terminus.It contains Val24-Gly559.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 60.8 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

MUC18/CD146; Gicerin; CD146; MCAM; MUC18

Target Information:

METCAM/MUC18 is an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family. It can carry out common functions of CAMs which is to perform intercellular interactions and interaction of cell with extracellular matrix in tumor microenvironment, to interact with various signaling pathways and to regulate general behaviors of cells.The above positive correlation is fortuitous; actually METCAM/MUC18 acts as a tumor and metastasis suppressor for the ovarian carcinoma cells.

Amino Acid Sequence: 

Val24-Gly559

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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