Product Name:

NebuSelect™ Recombinant Human MERTK/Mer, mFc-tag

Catalog#:

NBL-242310

Description:

NebuSelect™ Recombinant Human MERTK/Mer, mFc-tag(Cat#NBL-242310) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ala21-Ile505.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 78.9 kDa. Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result.

Target Name:

MERTK/Mer; MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12

Target Information:

MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.

Amino Acid Sequence: 

Ala21-Ile505

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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