Product Name:

NebuSelect™ Recombinant Mouse LRRN1, His-tag

Catalog#:

NBL-242336

Description:

NebuSelect™ Recombinant Mouse LRRN1, His-tag(Cat#NBL-242336) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser26-Ala631.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 69.28 kDa. Due to glycosylation, the protein migrates to 80-90 kDa based on Bis-Tris PAGE result.

Target Name:

LRRN1; Leucine-rich repeat neuronal protein 1; Neuronal leucine-rich repeat protein 1; NLRR-1; NLRR1; FIGLER3; KIAA1497; LRN

Target Information:

Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.

Amino Acid Sequence: 

Ser26-Ala631

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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