Product Name:

NebuSelect™ Recombinant Human LILRA3/CD85e, Avi-His-tag

Catalog#:

NBL-242353

Description:

NebuSelect™ Recombinant Human LILRA3/CD85e, Avi-His-tag(Cat#NBL-242353) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly24-Glu439.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 47.9 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.

Target Name:

LILRA3/CD85e; CD85e; HM31; HM43; ILT6; ILT-6; LILRA3; LIR4; LIR-4HM43e3

Target Information:

Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31,- is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Amino Acid Sequence: 

Gly24-Glu439

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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