Product Name:

NebuSelect™ Recombinant Biotinylated Human LAP (TGF beta 1) , Avi-His-tag

Catalog#:

NBL-242381

Description:

NebuSelect™ Recombinant Biotinylated Human LAP (TGF beta 1) , Avi-His-tag(Cat#NBL-242381) is expressed in HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu30-Arg278(C33S).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 31.4 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.

Target Name:

LAP (TGF beta 1); CEDLAP; DPD1; TGF beta1; TGFB; TGFB1; TGFbeta; TGF-beta-1

Target Information:

Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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