Product Name:

NebuSelect™ Recombinant Human JAM-A, His-tag

Catalog#:

NBL-242409

Description:

NebuSelect™ Recombinant Human JAM-A, His-tag(Cat#NBL-242409) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser28-Val238.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 24 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.

Target Name:

JAM-A; JAM-A; JAM-1; CD321; JAM; JCAM; JCAM1; KAT; PAM-1; F11 receptor; F11R; PAM-1KAT

Target Information:

junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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