Product Name:

NebuSelect™ Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer, His-tag

Catalog#:

NBL-242413

Description:

NebuSelect™ Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer, His-tag(Cat#NBL-242413) is expressed in HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 111.6(ITGAV)&76.6(ITGB8) kDa. Due to glycosylation, the protein migrates to 80-140 kDa based on Bis-Tris PAGE result.

Target Name:

Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer; Integrin alpha V beta 8；ITGAV&ITGB8

Target Information:

Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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