Product Name:

NebuSelect™ Recombinant Human IL-12 R beta 1/CD212, His-tag

Catalog#:

NBL-242441

Description:

NebuSelect™ Recombinant Human IL-12 R beta 1/CD212, His-tag(Cat#NBL-242441) is expressed in HEK293 with His tag at the C-Terminus.It contains Cys24-Glu540.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 58.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

IL-12 R beta 1/CD212; IL-12R-beta-1; IL-12RB1; IL12R; IL12RB; CD212; IL-12R subunit beta-1; IL-12R-BETA1; MGC34454

Target Information:

Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected by activation. Furthermore following its expression the IL12RB1 pre-mRNA is processed into either IL12RB1 Isoform 1 (IL12Rβ1, a positive regulator of IL12 responsiveness) or IL12RB1 Isoform 2 (a protein of heretofore unknown function).

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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