Product Name:

NebuSelect™ Recombinant Human ILDR2, hFc-tag

Catalog#:

NBL-242443

Description:

NebuSelect™ Recombinant Human ILDR2, hFc-tag(Cat#NBL-242443) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.

Target Name:

ILDR2; ILDR2; C1orf32; dJ782G3.1; RP4-782G3.2

Target Information:

Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.

Amino Acid Sequence: 

Leu21-Met184

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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