Product Name:

NebuSelect™ Recombinant Human IL-17C, Avi-His-tag

Catalog#:

NBL-242444

Description:

NebuSelect™ Recombinant Human IL-17C, Avi-His-tag(Cat#NBL-242444) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains His19-Val197.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 22.6 kDa. Due to glycosylation, the protein migrates to 25-28 kDa based on Bis-Tris PAGE result.

Target Name:

IL-17C; CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884

Target Information:

Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.