Product Name:

NebuSelect™ Recombinant Mouse IL-18BP, hFc-tag

Catalog#:

NBL-242453

Description:

NebuSelect™ Recombinant Mouse IL-18BP, hFc-tag(Cat#NBL-242453) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Thr29-Ala193.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 44.7 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.

Target Name:

IL-18BP; IL-18BP; Igifbp

Target Information:

Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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