Product Name:

NebuSelect™ Recombinant Human IL-7R alpha/CD127, hFc-tag

Catalog#:

NBL-242467

Description:

NebuSelect™ Recombinant Human IL-7R alpha/CD127, hFc-tag(Cat#NBL-242467) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu21-Gly236.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 51.6 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.

Target Name:

IL-7R alpha/CD127; IL-17R alpha; IL7Ra; CD127; CDW127; ILRA

Target Information:

Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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