
【产品概况】
产品名称:Human Siglec-3 / CD33 Antibody (IMGN779, Research Use)
产品编号:NBR-0871
针对靶点:Siglec-3 / CD33
抗体药商品名:IMGN779
抗体药描述:IMGN779 is a next-generation anti-CD33 ADC with anovel DNA-alkylating IGN payloadand a cleavable s-SPDB linker.Preclinical studies suggest potentantitumor activity and improvedsafety and tolerability compared withDNA-crosslinking payloads, allowingfor repeat dosing
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD22
Synonyms: SIGLEC-2; SIGLEC2
Target Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45.
Ensembl: ENSG00000012124
Uniprot: P20273