产品名称：Human Integrin a2b3 (ITGA2 & ITGB3) Antibody (Tadocizumab, Research Use)
产品编号：NBR-0879
针对靶点：Integrin a2b3 (ITGA2 & ITGB3)
抗体药商品名：Tadocizumab
抗体药描述：Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: ITGA2 & ITGB3
Synonyms: CD49B; CD61; GP3A; GPIIIa
Target Description: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. 
Ensembl:  ENSG00000164171; ENSG00000259207
Uniprot:  P17301; P05106